N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis

The abundant and reversible N6‐methyladenosine (m6A) RNA modification and its modulators have important roles in regulating various gene expression and biological processes. Here, we demonstrate that fat mass and obesity associated (FTO), as an m6A demethylase, plays a critical anti‐tumorigenic role...

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Detaylı Bibliyografya
Yayımlandı:J Cell Mol Med
Asıl Yazarlar: Zhuang, Changshui, Zhuang, Chengle, Luo, Xiaomin, Huang, Xinbo, Yao, Lv, Li, Jianfa, Li, Yawen, Xiong, Tiefu, Ye, Jing, Zhang, Fangting, Gui, Yaoting
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378205/
https://ncbi.nlm.nih.gov/pubmed/30648791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14128
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