N6‐methyladenosine demethylase FTO suppresses clear cell renal cell carcinoma through a novel FTO‐PGC‐1α signalling axis

The abundant and reversible N6‐methyladenosine (m6A) RNA modification and its modulators have important roles in regulating various gene expression and biological processes. Here, we demonstrate that fat mass and obesity associated (FTO), as an m6A demethylase, plays a critical anti‐tumorigenic role...

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Publicado en:J Cell Mol Med
Autores principales: Zhuang, Changshui, Zhuang, Chengle, Luo, Xiaomin, Huang, Xinbo, Yao, Lv, Li, Jianfa, Li, Yawen, Xiong, Tiefu, Ye, Jing, Zhang, Fangting, Gui, Yaoting
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6378205/
https://ncbi.nlm.nih.gov/pubmed/30648791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14128
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