Synthetic regulatory RNAs selectively suppress the progression of bladder cancer

The traditional treatment for cancer is lack of specificity and efficacy. Modular synthetic regulatory RNAs, such as inhibitive RNA (iRNA) and active RNA (aRNA), may overcome these limitations. Here, we synthesize a new iRNA to bind the upstream activating sequence (UAS) of a minimal promoter that d...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Zhuang, Chengle, Huang, Xinbo, Zhuang, Changshui, Luo, Xiaomin, Zhang, Xiaowei, Cai, Zhiming, Gui, Yaoting
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663129/
https://ncbi.nlm.nih.gov/pubmed/29084575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0626-x
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