Synthetic regulatory RNAs selectively suppress the progression of bladder cancer

The traditional treatment for cancer is lack of specificity and efficacy. Modular synthetic regulatory RNAs, such as inhibitive RNA (iRNA) and active RNA (aRNA), may overcome these limitations. Here, we synthesize a new iRNA to bind the upstream activating sequence (UAS) of a minimal promoter that d...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Zhuang, Chengle, Huang, Xinbo, Zhuang, Changshui, Luo, Xiaomin, Zhang, Xiaowei, Cai, Zhiming, Gui, Yaoting
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663129/
https://ncbi.nlm.nih.gov/pubmed/29084575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0626-x
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