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Optimized sequence library design for efficient in vitro interaction mapping

Sequence libraries that cover all k-mers enable universal, unbiased measurements of binding to both oligonucleotides and peptides. While the number of k-mers grows exponentially in k, space on all experimental platforms is limited. Here, we shrink k-mer library sizes by using joker characters, which...

詳細記述

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書誌詳細
出版年:Cell Syst
主要な著者: Orenstein, Yaron, Puccinelli, Robert, Kim, Ryan, Fordyce, Polly, Berger, Bonnie
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5661997/
https://ncbi.nlm.nih.gov/pubmed/28957657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.07.006
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