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Optimized sequence library design for efficient in vitro interaction mapping
Sequence libraries that cover all k-mers enable universal, unbiased measurements of binding to both oligonucleotides and peptides. While the number of k-mers grows exponentially in k, space on all experimental platforms is limited. Here, we shrink k-mer library sizes by using joker characters, which...
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| Veröffentlicht in: | Cell Syst |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5661997/ https://ncbi.nlm.nih.gov/pubmed/28957657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.07.006 |
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