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Efficient Design of Compact Unstructured RNA Libraries Covering All k-mers

Current microarray technologies to determine RNA structure or measure protein–RNA interactions rely on single-stranded, unstructured RNA probes on a chip covering together all k-mers. Since space on the array is limited, the problem is to efficiently design a compact library of unstructured ℓ-long R...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Orenstein, Yaron, Berger, Bonnie
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4752187/
https://ncbi.nlm.nih.gov/pubmed/26713687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2015.0179
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