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Design of shortest double-stranded DNA sequences covering all k-mers with applications to protein-binding microarrays and synthetic enhancers

Motivation: Novel technologies can generate large sets of short double-stranded DNA sequences that can be used to measure their regulatory effects. Microarrays can measure in vitro the binding intensity of a protein to thousands of probes. Synthetic enhancer sequences inserted into an organism’s gen...

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Autors principals: Orenstein, Yaron, Shamir, Ron
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694677/
https://ncbi.nlm.nih.gov/pubmed/23813011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt230
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