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Assessment of Algorithms for Inferring Positional Weight Matrix Motifs of Transcription Factor Binding Sites Using Protein Binding Microarray Data

The new technology of protein binding microarrays (PBMs) allows simultaneous measurement of the binding intensities of a transcription factor to tens of thousands of synthetic double-stranded DNA probes, covering all possible 10-mers. A key computational challenge is inferring the binding motif from...

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Bibliografiset tiedot
Päätekijät: Orenstein, Yaron, Linhart, Chaim, Shamir, Ron
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3460961/
https://ncbi.nlm.nih.gov/pubmed/23029415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046145
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