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DeCoDe: degenerate codon design for complete protein-coding DNA libraries

MOTIVATION: High-throughput protein screening is a critical technique for dissecting and designing protein function. Libraries for these assays can be created through a number of means, including targeted or random mutagenesis of a template protein sequence or direct DNA synthesis. However, mutageni...

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Bibliografische gegevens
Gepubliceerd in:Bioinformatics
Hoofdauteurs: Shimko, Tyler C, Fordyce, Polly M, Orenstein, Yaron
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7267834/
https://ncbi.nlm.nih.gov/pubmed/32176271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btaa162
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