Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia‐induced pulmonary hypertension

BACKGROUND AND PURPOSE: Sustained pulmonary vasoconstriction and excessive pulmonary vascular remodelling are two major causes of elevated pulmonary vascular resistance in patients with pulmonary arterial hypertension. The purpose of this study was to investigate whether chloroquine induced relaxati...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Wu, Kang, Zhang, Qian, Wu, Xiongting, Lu, Wenju, Tang, Haiyang, Liang, Zhihao, Gu, Yali, Song, Shanshan, Ayon, Ramon J, Wang, Ziyi, McDermott, Kimberly M, Balistrieri, Angela, Wang, Christina, Black, Stephen M, Garcia, Joe G N, Makino, Ayako, Yuan, Jason X‐J, Wang, Jian
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659991/
https://ncbi.nlm.nih.gov/pubmed/28849593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13990
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