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Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia‐induced pulmonary hypertension

BACKGROUND AND PURPOSE: Sustained pulmonary vasoconstriction and excessive pulmonary vascular remodelling are two major causes of elevated pulmonary vascular resistance in patients with pulmonary arterial hypertension. The purpose of this study was to investigate whether chloroquine induced relaxati...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Wu, Kang, Zhang, Qian, Wu, Xiongting, Lu, Wenju, Tang, Haiyang, Liang, Zhihao, Gu, Yali, Song, Shanshan, Ayon, Ramon J, Wang, Ziyi, McDermott, Kimberly M, Balistrieri, Angela, Wang, Christina, Black, Stephen M, Garcia, Joe G N, Makino, Ayako, Yuan, Jason X‐J, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5659991/
https://ncbi.nlm.nih.gov/pubmed/28849593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13990
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