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DNA topology in chromatin is defined by nucleosome spacing
In eukaryotic nucleosomes, DNA makes ~1.7 superhelical turns around histone octamer. However, there is a long-standing discrepancy between the nucleosome core structure determined by x-ray crystallography and measurements of DNA topology in circular minichromosomes, indicating that there is only ~1....
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| Publié dans: | Sci Adv |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Association for the Advancement of Science
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5659657/ https://ncbi.nlm.nih.gov/pubmed/29098179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1700957 |
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