Regulation of chromatin folding by conformational variations of nucleosome linker DNA

Linker DNA conformational variability has been proposed to direct nucleosome array folding into more or less compact chromatin fibers but direct experimental evidence for such models are lacking. Here, we tested this hypothesis by designing nucleosome arrays with A-tracts at specific locations in th...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Buckwalter, Jenna M., Norouzi, Davood, Harutyunyan, Anna, Zhurkin, Victor B., Grigoryev, Sergei A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766201/
https://ncbi.nlm.nih.gov/pubmed/28934465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx562
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