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Regulation of chromatin folding by conformational variations of nucleosome linker DNA

Linker DNA conformational variability has been proposed to direct nucleosome array folding into more or less compact chromatin fibers but direct experimental evidence for such models are lacking. Here, we tested this hypothesis by designing nucleosome arrays with A-tracts at specific locations in th...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Buckwalter, Jenna M., Norouzi, Davood, Harutyunyan, Anna, Zhurkin, Victor B., Grigoryev, Sergei A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5766201/
https://ncbi.nlm.nih.gov/pubmed/28934465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx562
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