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Topological polymorphism of nucleosome fibers and folding of chromatin

We discuss recent observations of polymorphic chromatin packaging at the oligonucleosomal level and compare them with computer simulations. Our computations reveal two topologically different families of two-start 30-nm fiber conformations distinguished by the linker length L; fibers with L ≈ 10n an...

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Publié dans:Biophys J
Auteurs principaux: Zhurkin, Victor B., Norouzi, Davood
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896024/
https://ncbi.nlm.nih.gov/pubmed/33460599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.01.008
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