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Topological polymorphism of nucleosome fibers and folding of chromatin

We discuss recent observations of polymorphic chromatin packaging at the oligonucleosomal level and compare them with computer simulations. Our computations reveal two topologically different families of two-start 30-nm fiber conformations distinguished by the linker length L; fibers with L ≈ 10n an...

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Detalles Bibliográficos
Publicado en:Biophys J
Main Authors: Zhurkin, Victor B., Norouzi, Davood
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896024/
https://ncbi.nlm.nih.gov/pubmed/33460599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2021.01.008
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