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Topological diversity of chromatin fibers: Interplay between nucleosome repeat length, DNA linking number and the level of transcription

The spatial organization of nucleosomes in 30-nm fibers remains unknown in detail. To tackle this problem, we analyzed all stereochemically possible configurations of two-start chromatin fibers with DNA linkers L = 10–70 bp (nucleosome repeat length NRL = 157–217 bp). In our model, the energy of a f...

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Détails bibliographiques
Publié dans:AIMS Biophys
Auteurs principaux: Norouzi, Davood, Katebi, Ataur, Cui, Feng, Zhurkin, Victor B.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5271602/
https://ncbi.nlm.nih.gov/pubmed/28133628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3934/biophy.2015.4.613
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