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Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays

The length of linker DNA that separates nucleosomes is highly variable, but its mechanistic role in modulating chromatin structure and functions remains unknown. Here, we established an experimental system using circular arrays of positioned nucleosomes to investigate whether variations in nucleosom...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bass, Mikhail V., Nikitina, Tatiana, Norouzi, Davood, Zhurkin, Victor B., Grigoryev, Sergei A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422092/
https://ncbi.nlm.nih.gov/pubmed/30630950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006412
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