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Nucleosome spacing periodically modulates nucleosome chain folding and DNA topology in circular nucleosome arrays

The length of linker DNA that separates nucleosomes is highly variable, but its mechanistic role in modulating chromatin structure and functions remains unknown. Here, we established an experimental system using circular arrays of positioned nucleosomes to investigate whether variations in nucleosom...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Bass, Mikhail V., Nikitina, Tatiana, Norouzi, Davood, Zhurkin, Victor B., Grigoryev, Sergei A.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422092/
https://ncbi.nlm.nih.gov/pubmed/30630950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006412
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