CTCF-dependent chromatin boundaries formed by asymmetric nucleosome arrays with decreased linker length

The CCCTC-binding factor (CTCF) organises the genome in 3D through DNA loops and in 1D by setting boundaries isolating different chromatin states, but these processes are not well understood. Here we investigate chromatin boundaries in mouse embryonic stem cells, defined by the regions with decrease...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Clarkson, Christopher T, Deeks, Emma A, Samarista, Ralph, Mamayusupova, Hulkar, Zhurkin, Victor B, Teif, Vladimir B
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868436/
https://ncbi.nlm.nih.gov/pubmed/31665434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz908
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