Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping

ATRX and MeCP2 belong to an expanding group of chromatin-associated proteins implicated in human neurodevelopmental disorders, although their gene-regulatory activities are not fully resolved. Loss of ATRX prevents full repression of an imprinted gene network in the postnatal brain and in this study...

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Bibliographic Details
Main Authors: Kernohan, Kristin D., Vernimmen, Douglas, Gloor, Gregory B., Bérubé, Nathalie G.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117782/
https://ncbi.nlm.nih.gov/pubmed/24990380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku564
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