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Analysis of neonatal brain lacking ATRX or MeCP2 reveals changes in nucleosome density, CTCF binding and chromatin looping

ATRX and MeCP2 belong to an expanding group of chromatin-associated proteins implicated in human neurodevelopmental disorders, although their gene-regulatory activities are not fully resolved. Loss of ATRX prevents full repression of an imprinted gene network in the postnatal brain and in this study...

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Bibliografische gegevens
Hoofdauteurs: Kernohan, Kristin D., Vernimmen, Douglas, Gloor, Gregory B., Bérubé, Nathalie G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117782/
https://ncbi.nlm.nih.gov/pubmed/24990380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku564
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