Novel nucleosomal particles containing core histones and linker DNA but no histone H1

Eukaryotic chromosomal DNA is assembled into regularly spaced nucleosomes, which play a central role in gene regulation by determining accessibility of control regions. The nucleosome contains ∼147 bp of DNA wrapped ∼1.7 times around a central core histone octamer. The linker histone, H1, binds both...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Cole, Hope A., Cui, Feng, Ocampo, Josefina, Burke, Tara L., Nikitina, Tatiana, Nagarajavel, V., Kotomura, Naoe, Zhurkin, Victor B., Clark, David J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Gene regulation, Chromatin and Epigenetics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4737182/
https://ncbi.nlm.nih.gov/pubmed/26400169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv943
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