Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma

Glioblastoma (GBM), the most aggressive brain cancer, is highly dependent on the mevalonate (MVA) pathway for the synthesis of lipid moieties critical for cell proliferation but the function and regulation of key intermediate enzymes like farnesyl-diphosphate synthase (FDPS), up to now, remained unk...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Abate, Mario, Laezza, Chiara, Pisanti, Simona, Torelli, Giovanni, Seneca, Vincenzo, Catapano, Giuseppe, Montella, Francesco, Ranieri, Roberta, Notarnicola, Maria, Gazzerro, Patrizia, Bifulco, Maurizio, Ciaglia, Elena
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658376/
https://ncbi.nlm.nih.gov/pubmed/29075041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14495-6
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak