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Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma
Glioblastoma (GBM), the most aggressive brain cancer, is highly dependent on the mevalonate (MVA) pathway for the synthesis of lipid moieties critical for cell proliferation but the function and regulation of key intermediate enzymes like farnesyl-diphosphate synthase (FDPS), up to now, remained unk...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658376/ https://ncbi.nlm.nih.gov/pubmed/29075041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14495-6 |
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