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Deregulated expression and activity of Farnesyl Diphosphate Synthase (FDPS) in Glioblastoma
Glioblastoma (GBM), the most aggressive brain cancer, is highly dependent on the mevalonate (MVA) pathway for the synthesis of lipid moieties critical for cell proliferation but the function and regulation of key intermediate enzymes like farnesyl-diphosphate synthase (FDPS), up to now, remained unk...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5658376/ https://ncbi.nlm.nih.gov/pubmed/29075041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14495-6 |
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