Prostaglandin-E(2) induces prorenin-dependent activation of (Pro)renin receptor and upregulation of Cyclooxygenase-2 in Collecting Duct Cells

BACKGROUND: Prostaglandin E2 (PGE(2)) regulates renin expression in renal juxtaglomerular cells. PGE(2) acts through E-prostanoid (EP) receptors in the renal collecting duct (CD) to regulate sodium and water balance. CD cells express EP1 and EP4, which are linked to protein kinase C (PKC) and protei...

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Publicat a:Am J Med Sci
Autors principals: Salinas-Parra, Nicolas, Reyes-Martinez, Cristian, Prieto, Minolfa C., Gonzalez, Alexis A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657580/
https://ncbi.nlm.nih.gov/pubmed/28918839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjms.2017.05.018
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