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Renin and the (Pro)renin Receptor in the Renal Collecting Duct:: Role in the Pathogenesis of Hypertension
The intrarenal renin-angiotensin-system (RAS) plays a critical role in the pathogenesis and progression of hypertension. In angiotensin (Ang) II-dependent hypertension, collecting duct renin synthesis and secretion are stimulated despite suppression of juxtaglomerular (JG) renin. This effect is medi...
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| Publicado en: | Clin Exp Pharmacol Physiol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454383/ https://ncbi.nlm.nih.gov/pubmed/25371190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12319 |
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