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Prostaglandin-E(2) induces prorenin-dependent activation of (Pro)renin receptor and upregulation of Cyclooxygenase-2 in Collecting Duct Cells
BACKGROUND: Prostaglandin E2 (PGE(2)) regulates renin expression in renal juxtaglomerular cells. PGE(2) acts through E-prostanoid (EP) receptors in the renal collecting duct (CD) to regulate sodium and water balance. CD cells express EP1 and EP4, which are linked to protein kinase C (PKC) and protei...
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| Publicado no: | Am J Med Sci |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5657580/ https://ncbi.nlm.nih.gov/pubmed/28918839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amjms.2017.05.018 |
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