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Angiotensin II-independent upregulation of Cyclooxygenase-2 by activation of the (pro)renin receptor in rat renal inner medullary cells

During renin-angiotensin system activation, cyclooxygenase-2 (COX-2)-derived prostaglandins attenuate the pressor and antinatriuretic effects of angiotensin II (AngII) in the renal medulla. The (pro)renin receptor (PRR) is abundantly expressed in the collecting ducts (CD) and its expression is augme...

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Autori principali: Gonzalez, Alexis A., Luffman, Christina, Bourgeois, Camille R. T., Vio, Carlos P., Prieto, Minolfa C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548040/
https://ncbi.nlm.nih.gov/pubmed/23184385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.196303
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