Angiotensin II-independent upregulation of Cyclooxygenase-2 by activation of the (pro)renin receptor in rat renal inner medullary cells

During renin-angiotensin system activation, cyclooxygenase-2 (COX-2)-derived prostaglandins attenuate the pressor and antinatriuretic effects of angiotensin II (AngII) in the renal medulla. The (pro)renin receptor (PRR) is abundantly expressed in the collecting ducts (CD) and its expression is augme...

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Hlavní autoři: Gonzalez, Alexis A., Luffman, Christina, Bourgeois, Camille R. T., Vio, Carlos P., Prieto, Minolfa C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3548040/
https://ncbi.nlm.nih.gov/pubmed/23184385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.196303
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