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Renal medullary cyclooxygenase-2 and (pro)renin receptor expression during angiotensin II-dependent hypertension
The (pro)renin receptor [(P)RR] upregulates cyclooxygenase-2 (COX-2) in inner medullary collecting duct (IMCD) cells through ERK1/2. Intrarenal COX-2 and (P)RR are upregulated during chronic ANG II infusion. However, the duration of COX-2 and (P)RR upregulation has not been determined. We hypothesiz...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4200301/ https://ncbi.nlm.nih.gov/pubmed/25143455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00267.2014 |
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