(Pro)renin Receptor Activation Increases Profibrotic Markers and Fibroblast-like Phenotype Through MAPK-dependent ROS Formation In Mouse Renal Collecting Duct Cells

Recent studies suggested that activation of the PRR upregulates profibrotic markers through reactive oxygen species (ROS) formation; however, the exact mechanisms have not been investigated in CD cells. We hypothesized that activation of the PRR increases the expression of profibrotic markers throug...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clin Exp Pharmacol Physiol
Hauptverfasser: Gonzalez, Alexis A., Zamora, Leonardo, Reyes-Martinez, Cristian, Salinas-Parra, Nicolas, Roldan, Nicole, Cuevas, Catherina A., Figueroa, Stefanny, Gonzalez-Vergara, Alex, Prieto, Minolfa C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5643228/
https://ncbi.nlm.nih.gov/pubmed/28696542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1440-1681.12813
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge