Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice

Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health. Our previous study revealed two genetically similar HPAI H5N8 viruses displaying completely different virulence in mice. However, the molecular b...

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Vydáno v:Vet Res
Hlavní autoři: Wang, Xiao, Chen, Sujuan, Wang, Dandan, Zha, Xixin, Zheng, Siwen, Qin, Tao, Ma, Wenjun, Peng, Daxin, Liu, Xiufan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657129/
https://ncbi.nlm.nih.gov/pubmed/29070059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-017-0471-0
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