Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice

Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health. Our previous study revealed two genetically similar HPAI H5N8 viruses displaying completely different virulence in mice. However, the molecular b...

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Bibliografski detalji
Izdano u:Vet Res
Glavni autori: Wang, Xiao, Chen, Sujuan, Wang, Dandan, Zha, Xixin, Zheng, Siwen, Qin, Tao, Ma, Wenjun, Peng, Daxin, Liu, Xiufan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657129/
https://ncbi.nlm.nih.gov/pubmed/29070059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-017-0471-0
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