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Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice
Abstract Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health. Our previous study revealed two genetically similar HPAI H5N8 viruses displaying completely different virulence in mice. However, the mo...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BMC
2017-10-01
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Colecção: | Veterinary Research |
Acesso em linha: | http://link.springer.com/article/10.1186/s13567-017-0471-0 |
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