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Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice

Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health. Our previous study revealed two genetically similar HPAI H5N8 viruses displaying completely different virulence in mice. However, the molecular b...

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Detalhes bibliográficos
Publicado no:Vet Res
Main Authors: Wang, Xiao, Chen, Sujuan, Wang, Dandan, Zha, Xixin, Zheng, Siwen, Qin, Tao, Ma, Wenjun, Peng, Daxin, Liu, Xiufan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5657129/
https://ncbi.nlm.nih.gov/pubmed/29070059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-017-0471-0
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