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Low fraction of the 222K PrP variant in the protease-resistant moiety of PrP(res) in heterozygous scrapie positive goats

The presence of lysine (K) at codon 222 has been associated with resistance to classical scrapie in goats, but few scrapie cases have been identified in 222Q/K animals. To investigate the contribution of the 222K variant to PrP(res) formation in natural and experimental Q/K scrapie cases, we applied...

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Библиографические подробности
Опубликовано в: :J Gen Virol
Главные авторы: Mazza, Maria, Guglielmetti, Chiara, Ingravalle, Francesco, Brusadore, Sonia, Langeveld, Jan P. M., Ekateriniadou, Loukia V., Andréoletti, Olivier, Casalone, Cristina, Acutis, Pier Luigi
Формат: Artigo
Язык:Inglês
Опубликовано: Microbiology Society 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656779/
https://ncbi.nlm.nih.gov/pubmed/28691895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000843
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