Low fraction of the 222K PrP variant in the protease-resistant moiety of PrP(res) in heterozygous scrapie positive goats

The presence of lysine (K) at codon 222 has been associated with resistance to classical scrapie in goats, but few scrapie cases have been identified in 222Q/K animals. To investigate the contribution of the 222K variant to PrP(res) formation in natural and experimental Q/K scrapie cases, we applied...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Mazza, Maria, Guglielmetti, Chiara, Ingravalle, Francesco, Brusadore, Sonia, Langeveld, Jan P. M., Ekateriniadou, Loukia V., Andréoletti, Olivier, Casalone, Cristina, Acutis, Pier Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2017
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656779/
https://ncbi.nlm.nih.gov/pubmed/28691895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000843
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