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Goats naturally devoid of PrP(C) are resistant to scrapie
Prion diseases are progressive and fatal, neurodegenerative disorders described in humans and animals. According to the “protein-only” hypothesis, the normal host-encoded prion protein (PrP(C)) is converted into a pathological and infectious form (PrP(Sc)) in these diseases. Transgenic knockout mode...
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| Pubblicato in: | Vet Res |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6954626/ https://ncbi.nlm.nih.gov/pubmed/31924264 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-019-0731-2 |
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