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Goat K(222)-PrP(C) polymorphic variant does not provide resistance to atypical scrapie in transgenic mice
Host prion (PrP(C)) genotype is a major determinant for the susceptibility to prion diseases. The Q/K(222)-PrP(C) polymorphic variant provides goats and mice with high resistance against classical scrapie and bovine spongiform encephalopathy (BSE); yet its effect against atypical scrapie is unknown....
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| 出版年: | Vet Res |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034450/ https://ncbi.nlm.nih.gov/pubmed/27659200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-016-0380-7 |
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