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Goat K(222)-PrP(C) polymorphic variant does not provide resistance to atypical scrapie in transgenic mice
Host prion (PrP(C)) genotype is a major determinant for the susceptibility to prion diseases. The Q/K(222)-PrP(C) polymorphic variant provides goats and mice with high resistance against classical scrapie and bovine spongiform encephalopathy (BSE); yet its effect against atypical scrapie is unknown....
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| Publicado no: | Vet Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034450/ https://ncbi.nlm.nih.gov/pubmed/27659200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13567-016-0380-7 |
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