The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch

Aims: Proliferative signaling involves reversible posttranslational oxidation of proteins. However, relatively few molecular targets of these modifications have been identified. We investigate the role of protein oxidation in regulation of SAMHD1 catalysis. Results: Here we report that SAMHD1 is a m...

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Dades bibliogràfiques
Publicat a:Antioxid Redox Signal
Autors principals: Mauney, Christopher H., Rogers, LeAnn C., Harris, Reuben S., Daniel, Larry W., Devarie-Baez, Nelmi O., Wu, Hanzhi, Furdui, Cristina M., Poole, Leslie B., Perrino, Fred W., Hollis, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2017
Matèries:
Original Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655415/
https://ncbi.nlm.nih.gov/pubmed/28398823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6888
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