The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch

Aims: Proliferative signaling involves reversible posttranslational oxidation of proteins. However, relatively few molecular targets of these modifications have been identified. We investigate the role of protein oxidation in regulation of SAMHD1 catalysis. Results: Here we report that SAMHD1 is a m...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Mauney, Christopher H., Rogers, LeAnn C., Harris, Reuben S., Daniel, Larry W., Devarie-Baez, Nelmi O., Wu, Hanzhi, Furdui, Cristina M., Poole, Leslie B., Perrino, Fred W., Hollis, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655415/
https://ncbi.nlm.nih.gov/pubmed/28398823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6888
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