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The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch

Aims: Proliferative signaling involves reversible posttranslational oxidation of proteins. However, relatively few molecular targets of these modifications have been identified. We investigate the role of protein oxidation in regulation of SAMHD1 catalysis. Results: Here we report that SAMHD1 is a m...

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Podrobná bibliografie
Vydáno v:Antioxid Redox Signal
Hlavní autoři: Mauney, Christopher H., Rogers, LeAnn C., Harris, Reuben S., Daniel, Larry W., Devarie-Baez, Nelmi O., Wu, Hanzhi, Furdui, Cristina M., Poole, Leslie B., Perrino, Fred W., Hollis, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655415/
https://ncbi.nlm.nih.gov/pubmed/28398823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6888
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