The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch

Aims: Proliferative signaling involves reversible posttranslational oxidation of proteins. However, relatively few molecular targets of these modifications have been identified. We investigate the role of protein oxidation in regulation of SAMHD1 catalysis. Results: Here we report that SAMHD1 is a m...

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Détails bibliographiques
Publié dans:Antioxid Redox Signal
Auteurs principaux: Mauney, Christopher H., Rogers, LeAnn C., Harris, Reuben S., Daniel, Larry W., Devarie-Baez, Nelmi O., Wu, Hanzhi, Furdui, Cristina M., Poole, Leslie B., Perrino, Fred W., Hollis, Thomas
Format: Artigo
Langue:Inglês
Publié: Mary Ann Liebert, Inc. 2017
Sujets:
Original Research Communications
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655415/
https://ncbi.nlm.nih.gov/pubmed/28398823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6888
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