The SAMHD1 dNTP Triphosphohydrolase Is Controlled by a Redox Switch

Aims: Proliferative signaling involves reversible posttranslational oxidation of proteins. However, relatively few molecular targets of these modifications have been identified. We investigate the role of protein oxidation in regulation of SAMHD1 catalysis. Results: Here we report that SAMHD1 is a m...

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Bibliografiset tiedot
Julkaisussa:Antioxid Redox Signal
Päätekijät: Mauney, Christopher H., Rogers, LeAnn C., Harris, Reuben S., Daniel, Larry W., Devarie-Baez, Nelmi O., Wu, Hanzhi, Furdui, Cristina M., Poole, Leslie B., Perrino, Fred W., Hollis, Thomas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2017
Aiheet:
Original Research Communications
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655415/
https://ncbi.nlm.nih.gov/pubmed/28398823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2016.6888
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