Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

BACKGROUND: Malaria, HIV/AIDS, and tuberculosis endemic areas show considerable geographical overlap, leading to incidence of co-infections. This requires treatment with multiple drugs, potentially causing adverse drug–drug interactions (DDIs). As anti-malarials are generally positively charged at p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Malar J
Egile Nagusiak: van der Velden, Maarten, Bilos, Albert, van den Heuvel, Jeroen J. M. W., Rijpma, Sanna R., Hurkmans, Evelien G. E., Sauerwein, Robert W., Russel, Frans G. M., Koenderink, Jan B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654082/
https://ncbi.nlm.nih.gov/pubmed/29061131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-2062-y
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