PfMDR2 and PfMDR5 are dispensable for Plasmodium falciparum asexual parasite multiplication but change in vitro susceptibility to anti-malarial drugs

BACKGROUND: Membrane-associated ATP binding cassette (ABC) transport proteins hydrolyze ATP in order to translocate a broad spectrum of substrates, from single ions to macromolecules across membranes. In humans, members from this transport family have been linked to drug resistance phenotypes, e.g.,...

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Bibliographic Details
Published in:Malar J
Main Authors: van der Velden, Maarten, Rijpma, Sanna R, Russel, Frans GM, Sauerwein, Robert W, Koenderink, Jan B
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350286/
https://ncbi.nlm.nih.gov/pubmed/25884516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0581-y
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