Resveratrol induces dephosphorylation of Tau by interfering with the MID1-PP2A complex

The formation of paired helical filaments (PHF), which are composed of hyperphosphorylated Tau protein dissociating from microtubules, is one of the pathological hallmarks of Alzheimer’s disease (AD) and other tauopathies. The most important phosphatase that is capable of dephosphorylating Tau at AD...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Schweiger, Susann, Matthes, Frank, Posey, Karen, Kickstein, Eva, Weber, Stephanie, Hettich, Moritz M., Pfurtscheller, Sandra, Ehninger, Dan, Schneider, Rainer, Krauß, Sybille
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653760/
https://ncbi.nlm.nih.gov/pubmed/29062069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12974-4
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