The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu

SHH (Sonic Hedgehog)-GLI signaling plays an important role during embryogenesis and in tumorigenesis. The survival and growth of several types of cancer depend on autonomously activated SHH-GLI signaling. A protein complex containing the ubiquitin ligase MID1 and protein phosphatase 2A regulates the...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Schweiger, Susann, Dorn, Stephanie, Fuchs, Melanie, Köhler, Andrea, Matthes, Frank, Müller, Eva-Christina, Wanker, Erich, Schneider, Rainer, Krauß, Sybille
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231658/
https://ncbi.nlm.nih.gov/pubmed/25278022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541219
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