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The E3 Ubiquitin Ligase MID1 Catalyzes Ubiquitination and Cleavage of Fu
SHH (Sonic Hedgehog)-GLI signaling plays an important role during embryogenesis and in tumorigenesis. The survival and growth of several types of cancer depend on autonomously activated SHH-GLI signaling. A protein complex containing the ubiquitin ligase MID1 and protein phosphatase 2A regulates the...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4231658/ https://ncbi.nlm.nih.gov/pubmed/25278022 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541219 |
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