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Inhibition of the MID1 protein complex: a novel approach targeting APP protein synthesis
Alzheimer’s disease (AD) is characterized by two neuropathological hallmarks: senile plaques, which are composed of amyloid-β (Aβ) peptides, and neurofibrillary tangles, which are composed of hyperphosphorylated tau protein. Aβ peptides are derived from sequential proteolytic cleavage of the amyloid...
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| 出版年: | Cell Death Discov |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5841321/ https://ncbi.nlm.nih.gov/pubmed/29531801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-017-0003-8 |
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