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CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects

Genome-editing involves the insertion, deletion, or replacement of DNA in the genome of a living organism using “molecular scissors.” Traditional genome editing with engineered nucleases for human stem cells is limited by its low efficiency, high cost, and poor specificity. The CRISPR system has rec...

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Détails bibliographiques
Publié dans:Mol Ther Nucleic Acids
Auteurs principaux: Zhang, Zhao, Zhang, Yuelin, Gao, Fei, Han, Shuo, Cheah, Kathryn S., Tse, Hung-Fat, Lian, Qizhou
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651489/
https://ncbi.nlm.nih.gov/pubmed/29246302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.09.009
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