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CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects
Genome-editing involves the insertion, deletion, or replacement of DNA in the genome of a living organism using “molecular scissors.” Traditional genome editing with engineered nucleases for human stem cells is limited by its low efficiency, high cost, and poor specificity. The CRISPR system has rec...
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| Publicado no: | Mol Ther Nucleic Acids |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5651489/ https://ncbi.nlm.nih.gov/pubmed/29246302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.09.009 |
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