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CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects

Genome-editing involves the insertion, deletion, or replacement of DNA in the genome of a living organism using “molecular scissors.” Traditional genome editing with engineered nucleases for human stem cells is limited by its low efficiency, high cost, and poor specificity. The CRISPR system has rec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Ther Nucleic Acids
Prif Awduron: Zhang, Zhao, Zhang, Yuelin, Gao, Fei, Han, Shuo, Cheah, Kathryn S., Tse, Hung-Fat, Lian, Qizhou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Gene & Cell Therapy 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651489/
https://ncbi.nlm.nih.gov/pubmed/29246302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.09.009
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